December 17, 2020
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In This Issue
 
Join      Rejoin     Renew
 
 
Track all things NAVBO
NAVBO Guided Tour
 
Meetings
 

Lymphatic Forum 2021
Online - May 31 to June 5
Vasculata 2021 in Boston, MA
 Dates to be determined

 
 
Corporate Partners

 

 

 

 

 

 
 
Corporate Members
 
 
 
VB2020 Supporters
 


 
 

 
 

 

 
 
VB2020 Exhibitors

 

 
 
 
 
VB2020 Guest Societies

 
 
Affiliated Journals
 
 
NAVBO Online Store
 
Help support our trainee scholarships
Any profits from the sale of these NAVBO items will help fund additional scholarships for students in the Advancing Young Voices Through Diversity and Inclusion Program. Thank you for your support!
Go to https://teespring.com/navbo-store to make your purchase! 
 
 
Double layered mask 
 
Coffee mug featuring the
NAVBO Online logo 
 
Canvas tote
Fanny pack
Fun NAVBO sticker!
 
Shop at Amazon?   
Help Support NAVBO 
 
Subscription for VBPA
 
Vascular Biology Publications Alert Now Available by Subscription
The NAVBO Vascular Biology Publications Alert will now be available to non-members for a $55 a year subscription.  If you would like to receive this alert, but are not a member, please contact Danielle at membership@navbo.org.
 
Partner Network Advantage on the NAVBO Job Board
 
Why post your job on NAVBO's career center rather than going directly to the larger job networks?
Pricing on the mass job boards can vary, but to get a job noticed you typically have to sponsor it for $5 - $10 per day, which can add up quickly especially since you also pay for each click the job gets. When you add it all together, you could be spending up to $45 per day on your job posting. But, when posting a job on NAVBO's career center, you simply pay a flat fee! The Premium package includes our Exclusive Extended Partner Network - which means the jobs are broadcast to sites like ZipRecruiter and Jobs2Careers and more for a flat fee.
 
With special member pricing, you can post a job for as low as $300 with this Partner Network. You never pay for each click, just the flat fee on the NAVBO career center. In addition, the Premium package includes a 60-day job posting making it a great value. The Premium packages also offer features like having your company's logo featured on the career center homepage, having your job appear first in search results, and more.
 
Post your open position now at www.navbo.org/jobs! 
 
NAVBO Privacy Policy
 
Your data privacy and security are important to NAVBO. To that end, we have updated our privacy policy to reflect recent privacy and security regulation implementations and changes. Please review our policy as time permits so you have a complete understanding of the data we have, why we have it, and how we use it.
 
Part of the updates relate directly to the European Union's new General Data Protection Regulation (GDPR) that went into place May 25.   The GDPR seeks to improve the transparency of data usage and give end users more control over their own data. We believe these changes are important and will be compliant with the GDPR regulations.
 
Contact NAVBO if you have any questions or to change your communication preferences.
 
 Please note, you can unsubscribe to this newsletter at anytime by clicking on the SafeUnsubscribe in the footer.
 
Wishing You All the Best for the Holiday Season
Happy Holidays and a Very Happy, Hopeful and Healthy New Year
I am sure we can all agree that 2020 was a year of great loss and we are all relieved to see it come to an end with some hope on the horizon.  We made the best of it and I am very thankful for all the NAVBO members that stepped up and provided the vascular biology community with wonderful content and great discussion in our Webinars, Journal Clubs, Summer Camp, other online activities and of course at Vascular Biology 2020.  Thank  you all for your continued support and participation.  NAVBO will continue to provide you with online events and activities.  
 
On behalf of the NAVBO Council, Committees, and staff, we wish you and your loved ones a happy and safe holiday and a 2021 filled with professional and personal growth, opportunities, and promise. 
Today's Journal Club
Join Us for Another Journal Club
Today's club will feature the paper: "Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis" 
Authors: Gabriel F. Alencar, Katherine M. Owsiany, Santosh Karnewar, Katyayani Sukhavasi, Giuseppe Mocci, Anh T. Nguyen, Corey M. Williams, Sohel Shamsuzzaman, Michal Mokry, Christopher A. Henderson, Ryan Haskins, Richard A. Baylis, Aloke V. Finn, Coleen A. McNamara, Eli R. Zunder, Vamsidhar Venkata, Gerard Pasterkamp, Johan Björkegren, Stefan Bekiranov, Gary K. Owens
Originally published 17 Jul 2020 - Circulation 2020;142:2045–2059
https://doi.org/10.1161/CIRCULATIONAHA.120.046672

The journal club features a 30-minute presentation by Dr. Mabruka Alfaidi, LSU Health Sciences Center - Shreveport, and a 30-minute Q&A with the audience. Our journal clubs are sponsored by the NAVBO Education Committee and today's journal club is bing moderated by committee member, William Hughes from the Medical College of Wisconsin.

Journal Clubs are limited to active/current NAVBO members.  The registration link can be found in the Journal Club's forum on our web site:  https://www.navbo.org/forum/12-20journal-club.  You can also post comments, questions, etc. here - before the presentation so that they can be addressed during the presentation and of course following the presentation to continue the conversation.

The session will be recorded, so register even if you can't attend the live presentation and receive a link to the recording automatically.

End of the Year - Make a Tax Deductible Contribution
Include NAVBO in Your Year End Giving
Please consider making a contribution to NAVBO.  Your donation will be used to support our many educational activities, such as our webinars and journal clubs, as well as some new online activities planned for 2021.  NAVBO is a 501(c)3 charitible organization.  To donate, please go to:
https://www.navbo.org/sponsor-support/donate
NAVBO Webinars
 
Upcoming
We are looking forward to our 2021 webinars! The year will begin with a webinar by Jason Fish of the University of Toronto on January 7, 2021.  Dr. Fish's presentation is titled, "Somatic oncogenic mutations in the endothelium drive vascular malformations."
For more details and to register, go to:

Next up is a webinar featuring Karen Hirschi, University of Virginia. Her presentation, titled "Regulation of Endothelial Cell Specialization" will take place on
February 18, 2021.   
For more details and to register, go to:
 
 
On March 4, we will welcome Guillermo Oliver of Northwestern University.    His presentation is titled, "Lymphatics in organ growth and repair." More information is available here: https://www.navbo.org/events/webinars/966-web032021
 
Mark your calendars for these webinars. And bookmark this page on our web site for more exciting 2021 webinars: https://www.navbo.org/events/webinars.
 
Honoring Stephen Schwartz
 
Special Tribute to Our Dear Friend
At the recent online NAVBO Town Hall (membership business meeting) on November 17, Dr. Michael Gimbrone gave a heartfelt tribute to the late Dr. Stephen Schwartz, who we lost in March of this year.  Dr. Gimbrone's account of Steve's life touches on not only Steve's brilliance as a scientist, but their long-time friendship. Watch the tribute.
 
More tributes to Steve can be found on our web site at
 
NAVBO has established a new award named for Dr. Schwartz, that will appropriately recognize outstanding mentorship.  Details will be online soon.
  
Request for Session Proposals
 
Organize and Moderate an Online Session
This is an opportunity to organize and moderate a session for NAVBO's New Online Symposia Series. We are seeking proposals from current regular members.

Our online meeting formats have proven to be very successful both before and during the pandemic; we believe that they will continue to be successful!
 
For several years we have sought session proposals for inclusion in the annual meeting.  However, this limited us to choosing only one or two proposals for presentation.  By moving this function to a bimonthly online forum, we will broaden the scope of the audience, provide opportunities to more members and provide the much requested free time to the annual meeting attendees.
 
We are asking our current regular members* to propose a 1.5 hour session with three speakers in a field that is relevant to the vascular biology community.  Proposals will be reviewed and selected by a committee.
 
We believe that this will be a great way to cover the broad scope of material within the vascular biology field.  
 
Submit your proposal today at:
(if the pdf doesn't open automatically, click the download icon within your browser, then choose Open with Adobe Acrobat)
 
* Current regular members: independent investigators whose membership is up to date.
Meet the NAVBO Twitter Team (from the December 3 issue)
 
NAVBO Twitter Team
Our team tweets and retweets as @vascularbiology helping to keep NAVBO's presence on Twitter (and in some cases, FaceBook, Instagram and LinkedIn) active and relevant.  We appreciate all they do for NAVBO  - especially promoting our meetings and webinars.  Yay Team! 
 
Please help them out by following NAVBO on Twitter - @vascularbiology and by retweeting NAVBO tweets.
 
Meet the team:
Mabruka Alfaidi,
Louisiana State University
Marie Billaud,
Brigham and Women's Hospital

Ondine Cleaver, 
UT Southwestern Medical Center

Jeff Hsu, 
UCLA

Sara Nunes de Vasconcelos,
University Health Network

Hao Yin,
Robart's Research Institute, Western University
Click on the image to follow them
 
Spotlight on Trainees (from the December 3 issue)
 
A new day for international education?
As the end of the Trump administration approaches, educators with a focus on international students are guardedly optimistic that a change in policy prioities at the very top will yield a more hospitable climate for those seeking a higher education experience in the US. Alongside this optimism, notes Elizabeth Redden in Inside Higher Ed, lies the concern that the serious damage done to America's reputation as a prime destination for international scholars will not be easy to reverse. Educators and international student advisors have contended with travel bans, executive orders, and obstructive regulatory actions. While President-elect Biden is expected to upend via executive order the ban that restricts travel from Muslim-majority countries, the fate of Trump's proposal to limit the duration of student visas remans uncertain. The rule would allow closer oversight of compliance with immigration laws, but is opposed by higher education groups owing to its burdensome new requirements on students and its incompatibility with academic program expectations.
 
Member News
 
Welcome to our New Members:
Brianna Alexander, Rutgers University
Cynthia Adjekukor, University of Calgary
Rita Anane-Wae, University of Virginia
Charles Ayemoba, University of Illinois at Chicago
Keith Battle, University of South Alabama
Travis Brady, Johns Hopkins University
Benney Endoni, University of Iowa
Xiaochen Fan, Stanford
Franklyn Hall, Johns Hopkins University
Katiannah Moise, Northwestern University
Emily Moreno, University of California, Davis
Brahmajothi Mulugu, Duke University
Lauren Thornton,Yale University
Michael Warkala, Rutgers University
 
If you have news to share with your colleagues, send it to membership@navbo.org.
 

Harvard Medical School Seminars in Vascular Biology
Organized by several NAVBO members (Peter Libby, Michael Gimbrone, Masanori Aikawa, Guillermo Garcia-Cardena, and Patricia D'Amore), this seminar series offers weekly talks on Thursdays at 4:30 PM (ET). Upcoming presentations:    
 
December 17         
Catherine "Lynn" Hedrick, PhD
La Jolla Institute for Immunology
Talk Title Pending
 
January 7         
Antonio Abbate, MD, PhD
Virginia Commonwealth University School of Medicine
Interleukin-1 Blockade in Cardiovascular Diseases
 
January 14         
Manuel Mayr, MD, PhD
King's College London
SARS-CoV-2 RNAemia and Associated Changes in the Plasma Proteome: Links between Systemic and Vascular Inflammation
 
January 21         
Mete Civelek, PhD
University of Virginia
Systems Genetics of Atherosclerosis-relevant Vascular Smooth Muscle Cell Phenotypes
 
January 28         
Alex Arenas, PhD
Universitat Rovira i Virgili
A Validated Single-Cell-Based Strategy to Identify Diagnostic and Therapeutic Targets in Complex Diseases
 
 
 Recent Publications by NAVBO Members
 

The N-Glycome regulates the endothelial-to-hematopoietic transition
Science
Definitive hematopoietic stem and progenitor cells (HSPCs) arise from the transdifferentiation of hemogenic endothelial cells (hemECs). The mechanisms of this endothelial-to-hematopoietic transition (EHT) are poorly understood. Read more

 

Lymphoangiocrine signals promote cardiac growth and repair
Nature
Recent studies have suggested that lymphatics help to restore heart function after cardiac injury. Here we report that lymphatics promote cardiac growth, repair and cardioprotection in mice.  Read more

 

Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells
Circulation Research
Rationale: Coronary artery disease (CAD) is a major cause of morbidity and mortality worldwide. Recent genome-wide association studies revealed 163 loci associated with CAD. However, the precise molecular mechanisms by which the majority of these loci increase CAD risk are not known.   Read more

 

Arterialization requires the timely suppression of cell growth
Nature
The formation of arteries is thought to occur by the induction of a highly conserved arterial genetic programme in a subset of vessels that will later experience an increase in oxygenated blood flow. The initial steps of arterial specification require both the VEGF and Notch signalling pathways. Read more

 
Industry News (from the December 3 issue)
 
NIH Center for Scientific Review mulls the future of reviewer confabs
How will study sections meet in the future? As Bruce Reed, Deputy Director of the CSR, notes in the Nov. 13 'Review Matters' blog, nearly all chartered review committee meetings were held in-person...until last March. Currently, the vast majority of all CSR review meetings are conducted via Zoom. Info from NIH reviewers, SROs, and other data sources show no sign that switching to Zoom was problematic review quality-wise. Still, reviewers and SROs tend to prefer in-person meetings for more individualized reasons. Looking forward, will meeting format affect scientists' willingness to participate as reviewers? To address this question, the CSR and the Office of Extramural Research plan to gather additional data from the February and March 2021 review meetings. Check out the details of their analyses thus far and share your ideas for how to improve Zoom review meetings. Please send your ideas to the CSR's Kristin Kramer, or add a comment on the blog linked above.
 
Enduring health inequities leave a legacy of distrust
A "...legacy of mistrust by people of color in health institutions, health professionals, researchers, and health policy-makers in the United States has existed for decades," writes former commissioner of Public Health for the District of Columbia Reed Tuckson in Science. This "disease of distrust" has had serious flare-ups in the COVID-19 pandemic, highlighting the reality that health inequity is widespread. Reed posits that establishment of trust in the medical community will be needed to remedy these inequities. John Holdren, director of the White House Office of Science and Technology Policy under President Obama, holds out hope that the incoming administration will pursue a more evidence-based approach to national health crises. For some communities, this will mean a restoration of trust; for others, especially those historically poorly served, it will mean building trust from the ground up. "We no longer have the luxury of staying in our laboratories," says Holdren. "We have to interact with broader society in ways that communicate what we're doing, why we're doing it, and why it matters."
 
Striking a blow against manuscript review as a precursor to publication
Beginning in July, 2021, the UK non-profit scientific communications platform eLife will focus its editorial activities on producing public reviews to be posted alongside preprints, thus reserving editorial review for manuscripts already available to the reading public. This "publish, then review" model of information disclosure springs from the recognition that nearly 70% of papers under review at eLife were already available on the preprint services bioRxiv, medRxiv or arXiv. In modifying their practices, eLife will be swimming against a current of authors who still are judged based on journal citations, the currency of their career advancement. Nevertheless, the journal states that their long-term goal is "...to move science away from the use of journal titles as the primary measure of the quality of research." Further, eLife aims to introduce more informative evaluation metrics to appear alongside articles either published in the journal or reviewed as preprints. In this model, review evolves to an ongoing process of curation.
 
Call for Papers
 
Special Issue "BMP Signaling and Beyond: Breaking the Cell Code of PAH"

https://www.mdpi.com/journal/cells/special_issues/BMP_Signaling_Cells.

Articles can be original research, method papers, clinical trial design, and/or reviews on the topic of PAH in general.  This is an exciting opportunity for trainees and early career investigators to gain visibility in the field by having their work published and promoted as part of this collection.  

Please feel free to share with anyone who might be interested in the topic.


Frontiers in Cardiovascular Medicine
Special Research Topics
 
 
What do we know about COVID-19 implications for cardiovascular disease?
Topic Editors: Hendrik Tevaearai Stahel, Masanori Aikawa, Shuyang Zhang, and Andrew F. James 
 
The coronavirus epidemic causes major cardiovascular complications. Underlying mechanisms, however, remain incompletely understood. Frontiers in Cardiovascular Medicine invite you to submit your article on this topic. We consider all types of manuscripts: fundamental basic science reports, translational or clinical studies, review articles and methodology papers.
 
We have already published 17 articles.  More submissions are currently under review.  Due to the popularity and the emerging nature of this topic, we decided to extend the deadline to December 31, 2020.  All articles submitted before this deadline will be published free of charge.  We encourage you to take advantage of this opportunity to publish your original study or review article in FCVM (Impact Factor 3.915). 
 
For more information, click here 
 
For questions, please contact Masanori Aikawa  maikawa@bwh.harvard.edu or the editorial office cardiovascularmedicine.editorial.office@frontiersin.org
 
Dear friends and colleagues,
 
 Jun Zhang, PhD (Associate Professor, Texas Tech University Health Sciences Center El Paso), is organizing a special issue entitled "Advancements in Cerebral Cavernous Malformations" in journal Vessel Plus (VP, ISSN 2574-1209).
 
This special issue aims to bring readers the up-to-date view of advancements in the scientific and technology innovations, translational and basic-science studies, and clinical trials of cerebral cavernous malformations. For more details about this special issue and the "Author Instructions", please visit the website at https://vpjournal.net/journal/special_detail/459.
 
Are you interested in contributing an article before February 15, 2021? If yes, please contact Jun Zhang (jun.zhang2000@gmail.com), the Guest Editor for this special issue, or Mavis Wei (mavis@vpjournal.net), the Managing Editor of VP. If you need additional information, please feel free to contact us.
 
VP is an online open access journal which was launched on March 31, 2017 by OAE Publishing Inc.  It waives the Article Processing Charge (APC) for all publications since launched. Thus, your manuscripts will be published totally free of charge once officially accepted after quick and rigorous peer-review. Meanwhile, all manuscripts published in VP will be immediately available online for free downloading and reading. Further, if the work is funded by NIH, we can deposit it in PubMed on your behalf.
 
Thank you for considering this invitation.
 
Dear friends and colleagues,
 
Ramani Ramchandran, PhD (Professor, Medical College of Wisconsin), is organizing a special issue entitled "The Road (Genes, Proteins, RNAs, and Signaling Pathways) Less Travelled in Vascular Biology" in journal Vessel Plus (VP, ISSN 2574-1209).
 
This special issue aims to provide readers with an up-to-date advancement in lesser-known genes, proteins and signaling pathways in vascular biology. Manuscripts related to concepts from these genes and proteins and their associated signaling pathways that connect into the well-established vascular ligand-receptor signaling systems are welcome. For more details about this special issue and the "Author Instructions", please visit the website at https://vpjournal.net/journal/special_detail/478.
 
Are you interested in contributing an article before December 31, 2020? If yes, please contact Ramani Ramchandran (rramchan@mcw.edu), the Guest Editor for this special issue, or Mavis Wei (mavis@vpjournal.net), the Managing Editor of VP. If you need additional information, please feel free to contact us.
 
VP is an online open access journal which was launched on March 31, 2017 by OAE Publishing Inc. It waives the Article Processing Charge (APC) for all publications since launched. Thus, your manuscripts will be published totally free of charge once officially accepted after quick and rigorous peer-review. Meanwhile, all manuscripts published in VP will be immediately available online for free downloading and reading. Further, if the work is funded by NIH, we can deposit it in PubMed on your behalf.
 
Thank you for considering this invitation.
 
Job Postings
Job Title
Company
Location
National Institutes of Health Bethesda, MD
UC Irvine Irvine, CA
Northwestern University Chicago, IL
 
Calendar of Events
 
June 18 - 22, 2021 Lymphatic Forum 2021
Oct. 24 - 28, 2021 Vascular Biology 2021
North American Vascular Biology Organization | bernadette@navbo.org | http://www.navbo.org
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Germantown, MD 20874-2211